Ndeipi Imaging Inonyanya Kushanda Pakuona Biochemical Kudzokororwa kweProstate Cancer: PET / CT kana mpMRI?

Zvinoenderana neazvino meta-analysis, positron emission tomography / computed tomography (PET / CT) uye yakawanda-parameter magineti resonance imaging (mpMRI) inopa zviyero zvekuonekwa zvakafanana mukuongorora kenza yeprostate (PCa) kudzoka.

Vatsvakurudzi vakawana kuti prostate specific membrane antigen (PSMA) PET / CT yaive nehuwandu hwekuonekwa kwehuwandu hwe69 muzana yekenza yeprostate kudzoka, zvichienzaniswa ne70 muzana ye mpMRI.

"Kune [kudzokerazve kwebiochemical], maitiro ese anoshanda. Zvigumisiro zvedu zvinoratidza kuti hapana misiyano yakakura muhuwandu hweDR (yezinga rekuona) pakati pemaitiro maviri ekufungidzira, uye mpMRI inonyanya kudhura paunenge uchichengetedza DR imwechete, "akanyora chidzidzo chemunyori L. Xu, akabatana neChikoro cheSchool of Mushonga. Hunan University of Traditional Chinese Medicine, Hunan, China uye vaanoshanda navo.

Nokuda kwePCa yemunharaunda, vanyori vekudzidza vakacherechedza kuti DR On mpMRI yaiva 10% yakakwirira (62% vs. 52%). Vatsvakurudzi vakawanawo kuti PSMA PET / CT yakaratidza 18% yekuvandudza muDR Paunenge uchiongorora lymph node metastasis (50% uye 32%, maererano). Zvisinei, hapana chimwe chezvakawanikwa chaive chakakosha, vanyori vekudzidza vakati.

Vatsvakurudzi vanotenda kuti hukuru hwekunzwa uye hutsananguro hunogona kupa PSMA PET / CT mukana muPCa staging uye kuona maronda maduku, asiwo vanobvuma kuti kuwanikwa kwenzira inyaya. Multi-parameter MRI inogona kubatsira pakuongorora kudzoka kwemunharaunda uye kliniki yakakosha PCa, asi vanyori vekudzidza vanobvuma kuti interobserver heterogeneity inogona kuva nyaya ne mpMRI.

Zvisinei, migumisiro yose yemeta-analysis inoratidza kuti nzira mbiri dzine basa pakuongorora PCa BCR, uye inonongedza kune ramangwana rinotarisirwa zvidzidzo zvinogona kupa kujekesa kukuru munyaya iyi.

Xu nevamwe vaaishanda navo vakasimbisa kukosha kukuru kwemhedzisiro yechidzidzo pakuita kwekiriniki. Vakataura kuti maitiro ekufananidza ekuongororwa kwePSMA PET / CT uye mpMRI anoratidza kushanda kwemaitiro maviri ekuona BCR muPCa varwere. Nekudaro, ivo vakasimbisa kukosha kwekuwedzera tsvakiridzo kuti vaongorore kugona, kuwanikwa, uye mutengo-unoshanda weaya maitiro ekufungidzira.

Pakukurukura zvisingakwanisi zvekudzidza, vanyori vakabvuma kuti saizi diki yevarwere ve290 yaive mhedzisiro yekutarisa kwavo kuongorora zvidzidzo zvekufananidza zvekuona BCR mukati memapoka evarwere mamwechete. Vakasimudzawo mukana wekurerekera mumhedzisiro nekuda kweakasiyana ekufungidzira maprotocol uye hunhu hwemurwere muzvidzidzo zvitanhatu zvavakaongorora.

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Nekuvandudzwa kwehunyanzvi hwekufungidzira zvekurapa, panobuda makambani mazhinji anogona kupa zvigadzirwa zvekufungidzira, senge majekiseni nemajekiseni.LnkMedtekinoroji yekurapa ndechimwe chazvo. Isu tinopa yakazara yakazara portfolio yeanobatsira diagnostic zvigadzirwa:CT jekiseni rimwe chete,CT kaviri musoro jekiseni,MRI jekiseniuyeDSA high pressure injector. Vanoshanda zvakanaka nemhando dzakasiyana-siyana dzeCT/MRI scanner dzakadai seGE, Philips, Siemens. Kunze kwejekiseni, isu tinopawo sirinji uye chubhu inoshandiswa kune akasiyana mabhureki ejekiseni anosanganisira Medrad/Bayer, Mallinckrodt/Guerbet, Nemoto, Medtron, Ulrich.
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